MY RESEARCH

 
 
 Photo credit: Ian Bowkett

Photo credit: Ian Bowkett

As a scientist, I'm interested in anything to do with the brain! With a background in the neurobiology of ageing and neurodegeneration, I'm particularly interested in what happens to our brains in degenerative diseases and old age and how these states effect the way our brains are wired.

I'm currently working on my PhD in neurosciences and axon biology. I grow brain cells in dishes in order to look at how defects in a cell maintenance mechanism called autophagy, (similar to defects found in the degenerative, muscle wasting disease known as motor neurone disease - or ALS-FTLD) can affect the function of the long, conductive arms of brain cells


For those of you who like the wordy version; I'm using in-vitro models of primary neuronal cell culture to understand how dysfunctional mutants of the autophagy protein, SQSTM1/P62, effect axonal development and degeneration in the context of Amyotrophic Lateral Sclerosis - Frontotemporal Lobar Dementia.


 
 

BRAINS IN DISH: Microscopy images from my lab work